Equilibrating metal-oxide cluster ensembles for oxidation reactions using oxygen in water.

Although many enzymes can readily and selectively use oxygen in water-the most familiar and attractive of all oxidants and solvents, respectively-the design of synthetic catalysts for selective water-based oxidation processes utilizing molecular oxygen remains a daunting task. Particularly problematic is the fact that oxidation of substrates by O2 involves radical chemistry, which is intrinsically non-selective and difficult to control. In addition, metallo-organic catalysts are inherently susceptible to degradation by oxygen-based radicals, while their transition-metal-ion active sites often react with water to give insoluble, and thus inactive, oxides or hydroxides. Furthermore, pH control is often required to avoid acid or base degradation of organic substrates or products. Unlike metallo-organic catalysts, polyoxometalate anions are oxidatively stable and are reversible oxidants for use with O2 (refs 8,9,10). Here we show how thermodynamically controlled self-assembly of an equilibrated ensemble of polyoxometalates, with the heteropolytungstate anion [AIVVW11O40]6- as its main component, imparts both stability in water and internal pH-management. Designed to operate at near-neutral pH, this system facilitates a two-step O2-based process for the selective delignification of wood (lignocellulose) fibres. By directly monitoring the central Al atom, we show that equilibration reactions typical of polyoxometalate anions keep the pH of the system near 7 during both process steps.     

Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA

Celiac disease is characterized by the presence of specific autoantibodies targeted against transglutaminase 2 (TG2) in untreated patients’ serum and at their production site in the small-bowel mucosa below the basement membrane and around the blood vessels. As these autoantibodies have biological activity in vitro, such as inhibition of angiogenesis, we studied if they might also modulate the endothelial barrier function. Our results show that celiac disease patient autoantibodies increase endothelial permeability for macromolecules, and enhance the binding of lymphocytes to the endothelium and their transendothelial migration when compared to control antibodies in an endothelial cell-based in vitro model. We also demonstrate that these effects are mediated by increased activities of TG2 and RhoA. Since the small bowel mucosal endothelium serves as a “gatekeeper” in inflammatory processes, the disease-specific autoantibodies targeted against TG2 could thus contribute to the pathogenic cascade of celiac disease by increasing blood vessel permeability.     

Flora of the Lee Creek valley, Alberta

The floristic composition of the Lee Creek valley in southwestern Alberta, Canada, is presented. The valley flora consists of 299 species of vascular plants representing 173 genera and 46 families. The flora is dominated by forbs (73 percent), followed by grasses (24 percent), shrubs (12 percent), and trees (11 percent). The valley of Lee Creek is divided into upper and lower sections on the basis of elevational, climatic, and biotic differences. Floristic richness of the Lee Creek valley is quite evenly divided between the upper and lower valleys: 105 species limited to the upper valley, 95 to the lower valley, and 99 species shared by both upper and lower valleys.     

Aquatic Oligochaeta (Annelida: Lumbriculidae, Haplotaxidae, Naididae, Tubificidae) of Utah

Thirty-six species of aquatic Oligochaeta (Lumbriculidae, Haplotaxidae, Naididae, Tubificidae) are now known form Utah. Aquatic habitats in 27 counties were sampled, with 32 oligochaete species identified. An additional 4 species were added from other published investigations. The majority of species are cosmopolitan and occur in other areas of North America. Nais barbata, N. alpina, and N. pardalis are reported from the western United States for the first time. Ilyodrilus frantzi was found to be a major component of the oliogochaete fauna in the Great Basin lentic environment. The North American distribution of Telmatodrilus vejdovskyi is extended significantly eastward. Tow undetermined species of Tubificidae are discussed.     

Effects of rangefire on soil algal crusts in semiarid shrub-steppe of the Lower Columbia Basin and their subsequent recovery

Effects of rangefire on soil algae in sagebrush steppe in the Lower Columbia Basin were studied. Dynamics of recovery of the soil algal community in the first two years following the fire were also documented. The study site was on the Arid Lands Ecology Reserve managed by Battelle Pacific Northwest Laboratory. Fire decreased the numbers of algae by more than an order of magnitude. Species composition in burned plots was similar to that in unburned plots, although some cyanophyte algae, particularly Nostoc commune , were decimated by the fire. Algal recovery took place in the winter months of the second year. Ninety taxa of algae were identified during the course of the study, over half of which were chlorophytes. Seasonal changes in the algal flora were also noted.     

Evaluation of a program to control hydatid disease in central Utah

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 st1\:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} A program to control hydatid disease in central Utah was evaluated by: (1) surveillance of infection in dogs and sheep, (2) questioning adult residents of two Sanpete County communities (Fountain Green and Spring City) about their knowledge of hydatid disease and their attitudes toward preventive measures, (3) interviewing local officials to evaluate the proposed implementation of proper community-wide measures, (4) analyzing records of prophylactic treatment of dogs with praziquantel, and (5) comparing scores of tests given to third and fourth grade students before and after they colored an educational pamphlet about hydatid disease. Infection rates of Echinococcus granulosus in dogs brought to volunteer diagnostic clinics dropped from 28.3 percent in 1972 to 1.0 percent in 1979, but increased to 9.8 percent in 1981. This last rise was due mainly to the fact that some dogs were examined that belonged to range sheepmen who had either not attended a field clinic recently or had never attended at all. Prevalence of the parasite in slaughtered sheep decreased steadily from 13.2 percent in 1972 to 2.8 percent in 1981. With regard to the questionnaire phase of the project, 87.3 percent and 84.3 percent of the respondents understood the role of dogs in the life cycle of E. granulosus in Fountain Green and Spring City, respectively. Over 50 percent of the respondents of these two communities had worked directly with sheep sometime in their life. In general, residents were more willing to practice preventive measures involving sheep than they were to implement measures involving dogs alone. However, many of the recommended community-wide preventive measures were not implemented. With the coloring book, students answered an average of 62.5 percent of the questions correctly before they colored the pamphlet and 83.3 percent afterward. Overall, our results suggest that residents of Sanpete County are knowledgeable about hydatid disease and its mode of transmission, and that, in general, progress has been made in control of hydatid disease in central Utah.       

Community Development and Renaissance Social Humanism: Some Lessons for Systems Science

Starting from the crisis in our communities—research has indicated it to be widely spread—the author explores the scientific tradition preceding the rise of modernism in order to draw out a more humane way of thinking that may help our contemporary societies. He discerns between two types of Renaissance humanism, one characterised by its cleverness, the other by its compassion and desire to restore dignity to the lives of people struggling to escape the clutches of medievalism. The father of the latter is Erasmus of Rotterdam and we follow the development of his conception of a social humanism as it branches out, through the work of his successors, into every scientific discipline, both natural and human. These disciplines are united by an embracing systemic idea of philosophy that unites the mind with the heart and which Erasmus called “Philosophia Christi”. We examine the two main pillars upon which this philosophy is built, love for our neighbour and education as the only legitimate instrument to change society, and the extraordinary impact it had on science and on communities living in the seventeenth century. We contrast this with the idea of power, the chosen instrument of modernity to transform society, and trace some of its tragic outcomes. We conclude by discussing the incorporation of an Erasmian type of social humanism into systems education and the future development of such programmes.     

New cooperative frequency domain differential modulation and demodulation

An innovative method of cooperative frequency domain differential modulation and demodulation is presented.This method applies the prior knowledge of channel propagation to selecting the variable differential length and carrying out frequency domain modulation.This strategy optimizes the design of system parameters to effectively improve the anti-interference ability of the differential system in time-varied multipath channel circumstance without making the execution more complicating.The simulations and comparisons demonstrate the proposed method is effective,and the results show that it is especially suitable for the fading channel with strong propagation and fast time-variation.     

Distribution and status of the yellow-faced pocket gopher in Kansas

Previous research suggests that the yellow-faced pocket gopher ( Cratogeomys castanops ) occupies a restricted range in western Kansas that is surrounded by the range of the plains pocket gopher ( Geomys bursarius ), which is regarded as a superior competitor. To determine whether the plains pocket gopher has encroached on the range of the yellow-faced pocket gopher in the past 35 years and to better understand the geographic relationships of these species, we trapped pocket gophers in western Kansas and collected soil texture and land cover data. We used ArcView 3.2 to map the distributions of these species in the study area, as well as the kinds of soil and land cover found in their potential home ranges. Although the distributions of the 2 species overlap, they are strictly parapatric. The apparent cause of this parapatric relationship is differential tolerance of soil textures. The distribution of the yellow-faced pocket gopher in Kansas is limited to just 7 counties divided into 2 populations, both surrounded by the distribution of the plains pocket gopher. We found no evidence that the range of the plains pocket gopher has expanded at the expense of the yellow-faced pocket gopher in the past 35 years. Thus, although the yellow-faced pocket gopher remains a “species of greatest conservation need” in Kansas because of agricultural threats, it evidently is not imperiled at this time.